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Symbol Name ID |
Tsc2
TSC complex subunit 2 MGI:102548 |
| Darker colors indicate more annotations |
| Human Phenotypes | Abnormal morphology of female internal genitalia |
| Disease(s) Associated with TSC2 | |
| lymphangioleiomyomatosis |
| Mouse Phenotypes | decreased male germ cell number |
increased Sertoli cell proliferation |
increased endometrial gland number |
abnormal testis morphology |
abnormal seminiferous tubule morphology |
abnormal seminiferous tubule epithelium morphology |
abnormal Sertoli cell morphology |
decreased testis weight |
small testis |
increased uterus leiomyoma incidence |
endometrium hyperplasia |
abnormal myometrium morphology |
increased uterus weight |
enlarged uterus |
abnormal spermatogenesis |
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| Availability | Mouse Genotype | |||||||||||||||
| Amhr2tm3(cre)Bhr/Amhr2+ Tsc2tm1.1Mjg/Tsc2tm1.1Mjg (conditional) |
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| Tsc2tm1.1Mjg/Tsc2tm1.1Mjg Pgrtm2(cre)Lyd/Pgr+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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